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Foldit for Science.

by Liz on May 12th, 2008

Protein folding as a competitive sport?

Sounds bizarre but researchers at the University of Washington are hoping that Foldit, a new computer game will help uncover the key to medical mysteries ranging from Alzheimer’s Disease to vaccines.

There are more than 100,000 different kinds of proteins in the human body. These proteins form cells, make up the immune system, and determine the speed of chemical reactions.

Scientists already know the genetic sequence of many of the proteins but not how they fold up into the complext shapes that play the crucial biological roles within the human body.

This is where Foldit comes in.

This computer game will allow players to manipulate on-screen images of protein chains and attempt to predict their folding patterns. Points are earned for every chemically stable folded protein they create. The more they create, the more they earn. The reward - maybe one day the Nobel Prize in Medicine according to the game’s creators.

In recent game trials, hundreds of players were provided with 40 protein puzzles (the folding solutions already known to the game makers) to solve and most of the players were able to find the correct structure faster than the computer could.

The next step is to provide players with proteins with unknown folding patterns and let them do the research in protein structure prediction through game playing.

Sounds like a unique form of scientific outsourcing.

This might be the one computer game that parents will encourage their children to play…

You can download it here.

(Source)

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